THE EFFECT OF DAEDALEA QUERCINA MUSHROOM EXTRACTS ON ANTIOXIDANT ENZYME ACTVITES | Atılım University Open Archive System
Bu kaydın yasal hükümlere uygun olmadığını düşünüyorsanız lütfen sayfa sonundaki Hata Bildir bağlantısını takip ederek bildirimde bulununuz. Kayıtlar ilgili üniversite yöneticileri tarafından eklenmektedir. Nadiren de olsa kayıtlarla ilgili hatalar oluşabilmektedir. MİTOS internet üzerindeki herhangi bir ödev sitesi değildir!
THE EFFECT OF DAEDALEA QUERCINA MUSHROOM EXTRACTS ON ANTIOXIDANT ENZYME ACTVITES
BROWSE_DETAIL_CREATION_DATE: 05-09-2016
BROWSE_DETAIL_IDENTIFIER_SECTION
BROWSE_DETAIL_TYPE: Thesis
BROWSE_DETAIL_SUB_TYPE: Masters
BROWSE_DETAIL_PUBLISH_STATE: Unpublished
BROWSE_DETAIL_FORMAT: PDF Document
BROWSE_DETAIL_LANG: English
BROWSE_DETAIL_SUBJECTS: Chemistry, Organic chemistry,
BROWSE_DETAIL_CREATORS: Rashuan, Amal Saad Mohamed (Author),
BROWSE_DETAIL_CONTRIBUTERS: İşgör, Sultan Belgin (Advisor),
BROWSE_DETAIL_URL: http://acikarsiv.atilim.edu.tr/browse/1936/
BROWSE_DETAIL_IDENTIFIER_OTHER: http://acikarsiv.atilim.edu.tr/browse/1936/10122042.pdf
BROWSE_DETAIL_TAB_FILE:
BROWSE_DETAIL_SHOW_FILE
BROWSE_DETAIL_SAVE_FILE
D.quercina mushroom, radical scavenging, antioxidant enzymes, DPPH assay, Catalase, Superoxide dismutase, Glutathione-S-transferase
Recently, there were great interest in use of mushrooms and their extracts as food supplements, since they accepted to enhance immune function, and hence promote health. They are playing important roles for treatment of numerous diseases from diabetes to various types of cancers. Today, most of the clinically effective pharmaceuticals are developed from chemical entities from mushroom in the history of medicine.In this study, total phenolic and flavonoid contents of methanol, ethanol and water extracts from D.quercina (L) Pers. was evaluated, for investigating their potential medicinal values against biological targets that are participating in the antioxidant defense system such as catalase (CAT), glutathione S-transferase (GST), and superoxide dismutase (SOD), and free radical scavenging activity. According to the results, the highest phenolic and flavonoid contents were found in the methanolicivextract of D.quercina (L) Persas 242 μg GEA /mL and 82.562μg QE/mL values, respectively. 2, 2-diphenyl-1-picrylhydrazyl (DPPH•) radical scavenging was observed with the methanol extract of D.quercina (L) Pers. with 50% inhibitory concentration value (IC50) of 0.081 g/L. The maximum GST and CAT enzyme inhibition activities were observed with methanol extract of D.quercina with 50% inhibitory concentration value (IC50) values of 0.05583g/L and 0.1458 g/L, respectively. The methanolic extract of D.quercina (L) Pers. showed less than 50% inhibitory effect on SOD enzyme activity and no IC50 value was available.
BROWSE_DETAIL_TAB_REFERENCES
BROWSE_DETAIL_TAB_REFERENCED_BYS